Novo Nordisk A/S - Share repurchase programme On 15 August 2008 Novo Nordisk initiated its share repurchase programme in accordance with the provisions of the European Commission's regulation no 2273/2003 of 22 December 2003, also referred to as the Safe Harbour rules. Under the programme Novo Nordisk will repurchase B shares for an amount of up to DKK 1.7 billion in the period from 15 August 2008 to 19 December 2008. Since the announcement as of 10 November 2008, the following transactions have been made under the programme: Number of Average Transaction shares purchase price value, DKK Accumulated, last announcement 3,376,500 956,623,504 10 November 2008 50,000 307.8600 15,393,000 11 November 2008 50,000 304.0800 15,204,000 12 November 2008 50,000 305.3800 15,269,000 13 November 2008 50,000 297.9500 14,897,500 14 November 2008 50,000 297.2600 14,863,000 Accumulated under the programme 3,626,500 1,032,250,004 Transactions related to Novo Nordisk's incentive programmes have resulted in a net sale by Novo Nordisk of 83,305 B-shares in the period from 10 November 2008 to 14 November 2008. The shares in these transactions were not part of the Safe Harbour repurchase programme. With the transactions stated above, Novo Nordisk owns a total of 24,593,285 treasury shares, corresponding to 3.9% of the share capital. The total amount of shares in the company is 634,000,000 including treasury shares. Novo Nordisk is a healthcare company and a world leader in diabetes care. In addition, Novo Nordisk has a leading position within areas such as haemostasis management, growth hormone therapy and hormone replacement therapy. Novo Nordisk manufactures and markets pharmaceutical products and services that make a significant difference to patients, the medical profession and society. With headquarters in Denmark, Novo Nordisk employs approximately 26,550 employees in 80 countries, and markets its products in 179 countries. Novo Nordisk's B shares are listed on the stock exchanges in Copenhagen and London. Its ADRs are listed on the New York Stock Exchange under the symbol 'NVO'. For more information, visit novonordisk.com. Further information: Media: Investors: Elin K Hansen Mads Veggerby Lausten Tel: (+45) 4442 3450 Tel: (+45) 4443 7919 ekh@novonordisk.com mlau@novonordisk.com Hans Rommer Tel: (+45) 4442 4765 hrmm@novonordisk.com In North America: Kasper Roseeuw Poulsen Sean Clements Tel: (+45) 4442 4471 Tel: (+1) 609 514 8316 krop@novonordisk.com secl@novonordisk.com Company Announcement no 75 / 2008