AstraZeneca prices a $2 billion bond issue

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| Source: AstraZeneca PLC
AstraZeneca prices a $2 billion bond issue

AstraZeneca PLC announces that yesterday it conducted a successful global bond
market transaction issuing a total of $2 billion of notes. The proceeds of the
issue will be used for debt refinancing and general corporate purposes. The
transaction, which is an SEC-registered global offering, consists of two
tranches:

$1 billion of 7-year fixed rate notes with a coupon of 1.95% and $1 billion of
30-year fixed rate notes with a coupon of 4%.
The notes will be issued under AstraZeneca’s existing automatic shelf
registration statement on Form F-3, which AstraZeneca filed with the US
Securities and Exchange Commission on 21 December 2010. Such registration
statement provides for the offer and sale from time to time of an indeterminate
amount of AstraZeneca’s debt securities and includes a prospectus which
investors should read to obtain more complete information. The offering was made
solely by means of a written prospectus forming part of the registration
statement.

A copy of the final prospectus supplement and accompanying prospectus relating
to the offering can be obtained by contacting Goldman Sachs & Co. at +1 866 471
2526, HSBC Securities (USA) Inc at +1 866 811 8049, J.P. Morgan Securities LLC
at +1 212 834 4533 or Morgan Stanley & Co. LLC at +1 866 718 1649.

– ENDS –

NOTES TO EDITORS

This announcement shall not constitute an offer to sell or the solicitation of
an offer to buy, nor shall there be any sale of these securities in any
jurisdiction in which such offer, solicitation or sale would be unlawful prior
to registration or qualification under the securities laws of any such
jurisdiction.

About AstraZeneca

AstraZeneca is a global, innovation-driven biopharmaceutical business with a
primary focus on the discovery, development and commercialisation of
prescription medicines for gastrointestinal, cardiovascular, neuroscience,
respiratory and inflammation, oncology and infectious disease. AstraZeneca
operates in over 100 countries and its innovative medicines are used by millions
of patients worldwide. For more information please visit: www.astrazeneca.com

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