Director/PDMR Shareholding

| Source: AstraZeneca PLC AstraZeneca PLC 

Transaction by Person Discharging Managerial Responsibilities

Disclosure Rule DTR 3.1.4

On 30 June 2014, Pascal Soriot, a Director of the Company, notified us that, on
30 June 2014, he purchased 46,200 AstraZeneca PLC Ordinary Shares of $0.25 each
at a price of 4345 pence per share.

A C N Kemp

Company Secretary

1 July 2014