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Source: TRACON Pharmaceuticals, Inc.

TRACON Pharmaceuticals Announces TRC694 Data Presentation at Upcoming AACR Annual Meeting

SAN DIEGO, March 27, 2017 (GLOBE NEWSWIRE) -- TRACON Pharmaceuticals (NASDAQ:TCON), a clinical stage biopharmaceutical company focused on the development and commercialization of novel targeted therapeutics for cancer, wet age-related macular degeneration and fibrotic diseases, today announced that TRC694 preclinical data will be presented at the upcoming American Association for Cancer Research (AACR) annual meeting to be held April 1-5, 2017, in Washington, D.C.

Lut Janssen and colleagues from Janssen Research & Development will present a poster featuring data from preclinical studies of TRC694. The presentation details are as follows:

Abstract Number:4199
Abstract Title:Inhibition of NF-kB inducing kinase (NIK) selectively abrogates NIK and TRAF3 mutant multiple myeloma tumor growth
Session Category:Experimental and Molecular Therapeutics
Location:Section 7, Poster Board Number 22
Date:Tuesday, April 4, 2017
Time:1:00pm – 5:00pm EDT 

The poster will be available on the Company’s website.

About TRC694

TRC694 is a novel, potent, orally bioavailable inhibitor of NF-kB inducing kinase (NIK) with the potential to be first-in-class that was discovered by Janssen and licensed by TRACON in September 2016. In pre-clinical studies, TRC694 selectively repressed P52/RelB mediated non-canonical NF-kB gene expression and inhibited NIK and TRAF3 mutant cell line proliferation in vitro and tumor growth in vivo. Genetic alterations leading to stabilization of NIK are found in a subset of B-cell malignancies: multiple myeloma, mantle-cell lymphoma (where it is associated with ibrutinib resistance), diffuse large B-cell lymphoma, Hodgkin’s lymphoma, and chronic lymphocytic leukemia.


TRACON develops targeted therapies for cancer, ophthalmic and fibrotic diseases. The Company’s clinical-stage pipeline includes: TRC105, an endoglin antibody that is being developed for the treatment of multiple cancers; DE-122, the ophthalmic formulation of TRC105 that is being developed in wet AMD through a collaboration with Santen Pharmaceutical Company Ltd.; and TRC102, a small molecule that is being developed for the treatment of lung cancer and glioblastoma. To learn more about TRACON and its product candidates, visit TRACON's website at

Company Contact:
Casey Logan
Chief Business Officer
(858) 550‐0780 ext. 236

Investor Contact:
Andrew McDonald
LifeSci Advisors LLC