Generex Biotechnology to Make Convertible Debenture Payment in Cash

Company Foregoes Issuing Equity at Current Level


WORCESTER, Mass., Nov. 12, 2008 (GLOBE NEWSWIRE) -- Generex Biotechnology Corporation (Nasdaq:GNBT) (http://www.generex.com) announced today that it intends to make the next payment, due on December 1, 2008, under its Senior Secured Convertible Notes in cash. The aggregate amount of that payment will be $1,376,666.66.

The Company is entitled to make monthly installment payments under the Notes in cash, or in shares of its common stock, or in a combination thereof. Payment in common stock is calculated at 90% of the trailing 20-trading day volume weighted average price (VWAP) of the stock.

"Although we would prefer to avoid applying our cash resources to the repayment of installment amounts, we feel that it is in the best interests of Generex and its stockholders to do so in respect of the December 1 payment," said Rose Perri, the Company's Chief Financial Officer. "The number of shares required to make that payment in stock would be significant and it is preferable to avoid that level of dilution."

The Company will assess the stock price, its cash reserves and budgetary requirements, as well as economic and market conditions generally, in order to make determinations in respect of the nature of each installment payment due in 2009. The notes mature on September 30, 2009.

About Generex Biotechnology Corporation

Generex is engaged in the research, development and commercialization of drug delivery systems and technologies. Generex has developed a proprietary platform technology for the delivery of drugs into the human body through the oral cavity (with no deposit in the lungs). The Company's proprietary liquid formulations allow drugs typically administered by injection to be absorbed into the body by the lining of the inner mouth using the Company's proprietary RapidMist device. The Company's flagship product, oral insulin (Generex Oral-lyn), which is available for sale in Ecuador and approved for sale in India for the treatment of subjects with Type-1 and Type-2 diabetes, is in Phase III clinical trials at several sites around the world. For more information, visit the Generex website at http://www.generex.com.

The Generex Biotechnology Corp. logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=3831

Safe Harbor Statement

This release and oral statements made from time to time by Generex representatives in respect of the same subject matter may contain "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. These statements can be identified by introductory words such as "expects," "plans," "intends," "believes," "will," "estimates," "forecasts," "projects," or words of similar meaning, and by the fact that they do not relate strictly to historical or current facts. Forward-looking statements frequently are used in discussing potential product applications, potential collaborations, product development activities, clinical studies, regulatory submissions and approvals, and similar operating matters. Many factors may cause actual results to differ from forward-looking statements, including inaccurate assumptions and a broad variety of risks and uncertainties, some of which are known and others of which are not. Known risks and uncertainties include those identified from time to time in the reports filed by Generex with the Securities and Exchange Commission, which should be considered together with any forward-looking statement. No forward-looking statement is a guarantee of future results or events, and one should avoid placing undue reliance on such statements. Generex undertakes no obligation to update publicly any forward-looking statements, whether as a result of new information, future events or otherwise. Generex cannot be sure when or if it will be permitted by regulatory agencies to undertake additional clinical trials or to commence any particular phase of clinical trials. Because of this, statements regarding the expected timing of clinical trials cannot be regarded as actual predictions of when Generex will obtain regulatory approval for any "phase" of clinical trials. Generex claims the protection of the safe harbor for forward-looking statements that is contained in the Private Securities Litigation Reform Act.



            

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