Apollomics Co-Founder and President, Sanjeev Redkar, Ph.D., to Speak at 23rd Annual R. Bryan Miller Symposium

Dr. Redkar to discuss importance of HGF/cMET pathway, which can play critical role in origin of several cancers


FOSTER CITY, Calif., April 11, 2023 (GLOBE NEWSWIRE) -- Apollomics Inc. (Nasdaq: APLM), a late-stage clinical biopharmaceutical company developing multiple oncology drug candidates to address difficult-to-treat and treatment-resistant cancers, today announced that the company’s Co-Founder and President, Sanjeev Redkar, MBA, Ph.D., will speak at the 23rd Annual R. Bryan Miller Symposium, an event exploring the interface of chemical biology and organic chemistry in honor of Professor R. Bryan Miller, at the University of California, Davis on April 14, 2023.

Dr. Redkar will deliver the presentation, titled, "The HGF/cMet Pathway in Cancer – Early Development to Clinical Evidence,” at 11 a.m. PST at the UC Davis Conference Center. Following the event, a copy of the presentation will be made available on the Apollomics website here.

In cancer cells, aberrant HGF/c-Met axis activation, which is closely related to c-Met (or “cMET”) gene mutations, overexpression and amplification, promotes tumor growth and proliferation. HGF/c-Met axis also plays an important role in a cancer cell’s ability to develop resistance to certain targeted therapies that affect other signaling pathways. Therefore, c-Met and its associated signaling pathways are potentially clinically important therapeutic targets. Apollomics is developing a small molecule, orally bioavailable and highly specific c-Met inhibitor, APL-101, for the treatment of non-small cell lung cancer (NSCLC) and brain tumors.

Dr. Redkar will be joined by other distinguished speakers, including:

  • Paula T. Hammond, Ph.D.: David H. Koch Chair Professor in Engineering and the Head of the Department of Chemical Engineering at the Massachusetts Institute of Technology (MIT)
  • David R. Liu, Ph.D.: Vice-Chair of the Faculty at the Broad Institute of Harvard and MIT. He is also the founder or co-founder of multiple therapeutics and biotechnology companies, including Chroma Medicine, Exo Therapeutics, Pairwise Plants, Editas Medicine, Beam Therapeutics, Resonance Medicine, Nvelop Therapeutics and Prime Medicine.

The full list of speakers and schedule of the 2023 Miller Symposium can be found here: R. Bryan Miller Symposium | Chemistry (ucdavis.edu)

About Apollomics Inc. 

Apollomics Inc. is an innovative clinical-stage biopharmaceutical company focused on the discovery and development of oncology therapies with the potential to be combined with other treatment options to harness the immune system and target specific molecular pathways to inhibit cancer. Apollomics currently has a pipeline of nine drug candidates across multiple programs, six of which are currently in the clinical stage of development. Apollomics’ lead programs include investigating its core product, vebreltinib (APL-101), a potent, selective c-Met inhibitor for the treatment of non-small cell lung cancer and other advanced tumors with c-Met alterations, which is currently in a Phase 2 multicohort clinical trial in the United States, and developing an anti-cancer enhancer drug candidate, uproleselan (APL-106), a specific E-Selectin antagonist that has the potential to be used adjunctively with standard chemotherapy to treat acute myeloid leukemia and other hematologic cancers, which is currently in Phase 1 and Phase 3 clinical trials in China.

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