Recipients of the 5th Annual Novartis Award in Diabetes honored today


Judging panel continues to praise 'outstanding' quality of nominations received

Basel, 16 June 2003 - Novartis honors the recipients of the 2003 Novartis Award in Diabetes. Four awards will be given today to clinical investigators judged to have made exceptional contributions to the field of diabetes. This year's Award recipients are Professor Jørn Nerup, Professor Ralph DeFronzo, Professor Andrew Hattersley and Dr. Lloyd Aiello.

The selection panel, comprised of independent internationally-recognized diabetes experts, selected two recipients in each of the categories: Long-Standing Achievement and Young Investigator.

Professor Eberhard Standl, Chair of the selection panel, said "We were again extremely impressed by the quality of the nominations this year. The recipients have conducted outstanding research, crucial to advancing our knowledge of diabetes. Their contributions have already had and will have a major impact on diabetes treatment and on the life of millions of people around the world who are affected by diabetes."

The Long-Standing Achievement Awards will be presented to Professor Jørn Nerup of Denmark and Professor Ralph A. DeFronzo of the USA for their exceptional and sustained achievements in clinical research, education and clinical practice.

Professor Nerup is Chief Physician at Steno Diabetes Canter, Gentofte, Denmark and adjunct Professor at the University of Copenhagen School of Medicine. As the leader of a laboratory dedicated to the study of Type 1 diabetes pathogenesis he has been the mentor of numerous young researchers and clinicians. Professor Nerup obtained the first experimental and clinical demonstration that type 1 diabetes is an autoimmune disease and discovered its association with HLA as a genetic and pathogenetic marker of distinction from Type 2 diabetes and has published over 400 scientific articles. He is also a dedicated physician, spending half his time caring for patients.

Professor DeFronzo is Professor of Medicine and the Chief, Diabetes Division, at the University of Texas Health Science Center at San Antonio, and Deputy Director, Texas Diabetes Institute, USA. He has published over 400 scientific articles and is acknowledged for his dedication to the training of over 150 young clinical investigators. Professor DeFronzo has made major contributions to the development of novel technologies that have greatly advanced knowledge about the pathogenesis and metabolic abnormalities that characterize type 2 diabetes mellitus, the insulin resistance syndrome, obesity, hypertension, dyslipidemia and others.

The Young Investigator Award recognizes innovative patient-oriented research in the fields of physiology, path physiology or epidemiology of diabetes and its complications. Awards will be presented to Professor Andrew T. Hattersley of the UK and Dr. Lloyd P. Aiello of the USA.

Professor Hattersley is Professor in Molecular Medicine and a Consultant Diabetologist at the Peninsula Medical School in Exeter, UK. He is an international leader in the field of the genetics of diabetes, particularly the monogenic form of diabetes, maturity-onset diabetes of the young (MODY) publishing over 140 scientific papers. Professor Hattersley's work has been said to go "from patients to genes and back again". He has defined genes that cause diabetes and is now pioneering using molecular genetic information in the diabetic clinic to improve the diagnosis and treatment of patients.

Dr. Aiello is the Associate Director of the Beetham Eye Institute at Joslin Diabetes Centre, one of the leading diabetes ophthalmologic research and clinical centers in the world. He published the first extensive study showing that the level of vascular endothelial growth factor (VEGF) correlated with the severity of diabetic retinopathy. Dr. Aiello has published numerous papers in top rated journals, including The New England Journal of Medicine, Proceedings of the National Academy of Science, Journal of Clinical Investigation, Diabetes Care and many others.

"We, at Novartis, honor this year's recipients for their personal and professional commitment to diabetes," said Dr. James Shannon, Global Head of Clinical Development and Medical Affairs from Novartis. "Now in its 5th year, we hope that the Novartis Award in Diabetes will continue to inspire researchers from around the world to strive for the highest standards in diabetes treatment and clinical research."

Award Recipients will be presented with their Awards and $25,000 US each by Panel members during a Gala Presentation Dinner to be held tonight at the Musee Conti, New Orleans.

Novartis Commitment to Diabetes
This international award is one of many activities that Novartis is supporting to help increase awareness of and urgency for innovation in diabetes research, education and clinical practice. Novartis is constantly exploring new approaches for the treatment of type 2 diabetes, including the novel insulin secretion agent, Starlix (nateglinide), which has been approved in many countries around the world. Nateglinide is licensed to Novartis Pharma AG from Ajinomoto Co., Inc.

Novartis AG (NYSE: NVS) is a world leader in pharmaceuticals and consumer health. In 2002, the Group's businesses achieved sales of USD 20.9 billion and a net income of USD 4.7 billion. The Group invested approximately USD 2.8 billion in R&D. Headquartered in Basel, Switzerland, Novartis Group companies employ about 77 200 people and operate in over 140 countries around the world. For further information please consult http://www.novartis.com.

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