Protherics PLC Notification of Major Interest in Shares London, UK; Brentwood, TN, US; 26 February 2007 - Protherics PLC ("Protherics" or the "Company"), the international biopharmaceutical company focused on critical care and cancer, announces that the following notification of interest in the ordinary share capital of the Company was received on 23 February 2007 from AMVESCAP PLC. 1. Reason for the notification (please tick the appropriate box or boxes) An acquisition or disposal of voting rights x An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights Other (please specify):___________________________________________ 2. Full name of person(s) subject to the AMVESCAP PLC notification obligation: 3. Full name of shareholder(s) (if different from 2.): 4. Date of the transaction (and date on which the 20 February 2007 threshold is crossed or reached if different): 5. Date on which issuer notified: 21 February 2007 6. Threshold(s) that is/are crossed or reached: 10% 7. Notified details: A: Voting rights attached to shares Class/type of Situation previous to Resulting situation after the triggering transaction shares the Triggering transaction if possible using Number of Number of Number of Number of voting rights % of voting rights the ISIN CODE Shares Voting shares Rights Direct Direct Indirect Direct Indirect Ordinary Shares 30,886,678 30,886,678 35,740,354 35,740,354 10.54% 2p GB0007029209 B: Financial Instruments Resulting situation after the triggering transaction Type of financial Expiration date Exercise/ Conversion Number of voting rights % of voting instrument Period/ Date that may be acquired if rights the instrument is exercised/ converted. Total (A+B) Number of voting rights % of voting rights 35,740,354 10.54% 8. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable : Chase Nominees - 7,520,443 Vidacos Nominees - 28,104,599 Northern Trust Company (London) - 115,312 Proxy Voting: 9. Name of the proxy holder: 10. Number of voting rights proxy holder will cease to hold: 11. Date on which proxy holder will cease to hold voting rights: 12. Additional information: | Ends | For further information please contact: Protherics Nick Staples, Director of Corporate Affairs +44 (0) 7919 480510 Julie Vickers, Company Secretary +44 (0)1928 518010 Financial Dynamics - press enquiries London: Ben Atwell, Anna Keeble +44 (0) 20 7831 3113 New York: John Capodanno, Jonathan Birt +1 212 850 5600 Or visit www.protherics.com This information is provided by RNS The company news service from the London Stock Exchange
Protherics PLC announces Holding(s) in Company
| Source: Protherics PLC
Cheshire, UK -- (MARKET WIRE) -- February 26, 2007 --