Contact Information: Contacts: Kevin Krenitsky Chief Executive Officer BioServe 301-470-3362 Constantine Theodoropulos Boston Communications 617-619-9801
BioServe Selected by Specialized Clinical Center of Research for Study on Thoracic Aortic Disease
Novel Genetic Study to Identify Genes Predictive of the Development and Progression of Thoracic Aortic Disease
| Source: BioServe
BELTSVILLE, MD--(Marketwire - June 18, 2007) - BioServe today announced that it has been
selected by Houston-based Specialized Clinical Center of Research (SCCOR)
for a novel study aimed at identifying the genetic cause of thoracic aortic
disease. The SCCOR is a collaborative program by University of Texas Health
Science Center Houston, Baylor College of Medicine and University of Texas
Medical Branch. Under terms of the agreement, BioServe will provide the
SCCOR researchers with access to certain unique sample sets from its Global
Repository of over 600,000 human DNA, tissue and serum samples linked to
detailed clinical and demographic data to assist in identifying genes that
are predictive of the development and progression of thoracic aortic
diseases. Thoracic aortic disease is the 15th leading cause of death in the
United States, with aortic dissections being the 13th leading cause of
death in people between the ages of 55 and 64.
"Through this landmark study we hope to define DNA sequence variants in a
few target genes and their interacting environmental risk factors that are
responsible for a significant proportion of the thoracic aortic diseases.
By identifying the underlying and specific genetic causes of thoracic
aortic disease we will provide doctors with the ability to predict which
patients are at higher risk of aortic rupture, and treat them earlier,"
said Xin Li Wang, a professor and director in the cardiothoracic research
laboratory in the division of cardiothoracic surgery of the Michael E.
DeBakey Department of Surgery at Baylor College of Medicine.
Wang added, "BioServe is an ideal partner for this important study. They
provide us with a comprehensive Biobank linked to extensive clinical and
demographic data against which to run our diseased case samples and a team
highly experienced in running large scale genetic studies. This unique
combination of capabilities will enable us to accelerate our research to
find genetic markers predictive of the disease."
Kevin Krenitsky, Chief Executive Officer of BioServe, said, "We are excited
to partner with the Houston SCCOR on this significant genetic study of
thoracic aortic disease. Our work with the Houston SCCOR will contribute to
the genetic understanding of a debilitating disease, and provide the
foundation for improved risk assessment and early intervention, taking us a
step closer to a personalized medicine regimen."
The study is underwritten by a 5-year inter-institutional grant from the
National Heart, Lung and Blood Institute (NHLBI) and is being carried out
at Specialized Center for Clinically Oriented Research in Thoracic Aortic
Aneurysms and Dissections in the Texas Medical Center. The center is
directed by Dr. Dianna Milewicz from University of Texas Health Science
Center at Houston (UTHSCH), and co-directed by Dr. Joseph Coselli from
Texas Heart Institute, Baylor College of Medicine and Dr. Hazim Safi from
UTHSCH. Other participating institutions are The University of Texas
Medical Branch (UTMB).
About BioServe
BioServe is a leader in the processing, development, and validation of
diagnostic tests for the practice of personalized, predictive and
preventive medicine. Leading pharma, biotech and diagnostic firms
collaborate with BioServe to identify and validate markers that cause
disease while correlating clinical and molecular data to develop new
diagnostic tests promoting wellness around the world. BioServe offers the
Global Repository®, a growing library of over 600,000 human DNA, tissue
and serum samples linked to detailed clinical and demographic data from
140,000 consented and anonymized patients from four continents. Leveraging
BioServe's robust genomic analytical services, technology, Global
Repository and CLIA-certified laboratory, collaborators gain a complete,
highly efficient platform for processing diagnostic test results and
identifying genomic markers for powerful new assays. BioServe has
headquarters in Beltsville, MD and Hyderabad, India. For more information
please visit www.bioserve.com or call 301-470-3362.