Dublin, Nov. 12, 2018 (GLOBE NEWSWIRE) -- The "Global NGS Informatics and Clinical Genomics Market: Focus on Product Types (LIMS, Data Analysis and Interpretation Tools, and Storage and Computing Solutions), End Users, and Regional Analysis for 21 Countries: Analysis and Forecast (2018-2028)" report has been added to ResearchAndMarkets.com's offering.
The global NGS informatics and clinical genomics market is composed of tools, software solutions and services catering for the data analysis needs of the NGS market. Despite the technological advancement in the field of next generation sequencing, analysing huge datasets coming out of sequencers remains a major challenge in the industry that prevents the NGS technology to be used as a routine technique.
There are three significant forms of NGS data analysis: primary, secondary, and tertiary analysis. The software platforms or tools catering for NGS data analysis either perform primary, secondary, and tertiary data analysis. However, there are software packages available which provide end to end (primary to tertiary) data analysis solutions. Some of the major analysis performed by NGS software tools include image acquisition, quality control, base calling, alignment to a reference genome, variant calling, and biological interpretation.
In the primary analysis stage, the raw data is converted to sequence data wherein the base pairs in a genome are typically identified by laser excitation or fluorescence detection. A primary data analysis tool is a part of sequencing instruments and is typically installed on the local hardware systems supporting sequencing instruments. The resultant of this data analysis stage is usually a FASTQ file (string of characters: A, C, T, G, and N). In the secondary data analysis stage, reads generated (short genomic sequences) are aligned against a reference genome.
Once the file is aligned, a BAM file is generated which is subject to further refinement steps such as flagging or filtering of duplicate reads, recalibration of quality scores (in the first stage), and variant calling with the help of various statistical modelling techniques. The variant calling step determines the point of difference between the sample and the reference genome. The last and the most complex and time-consuming phase of NGS data analysis is tertiary analysis. This stage aims at identifying which variants in a sample are benign, pathogenic, or VUS (variant of unknown clinical significance). The complexity of the stage can be understood from the fact that one human exome may have approximately 3.2 million variants and interpretation of each of the variants become a daunting task for the industry.
The market report is well-designed to provide an all-inclusive field of vision about the global NGS informatics and clinical genomics market in terms of various factors, such as recent trends, technological advancements, competitive landscape, and regulatory environment of the market. The scope of this report is centred upon conducting a detailed study of the solutions allied with the global NGS informatics and clinical genomics market. The market has been segmented into Technology Products', End Users', and Region'. The report presents the reader with an opportunity to unlock comprehensive insights with respect to the market and helps in forming well-informed strategic decisions. The research uncovers some of the substantial parameters that must be taken into consideration before entering the market.
This research report aims at answering various aspects of the global NGS informatics and clinical genomics market with the help of the key factors driving the market, challenges, and threats that can possibly inhibit the overall growth of the market and the current investment opportunities that are going to shape the future trajectory of the market expansion. The study considers the growth-share matrix model for a comprehensive study of the global NGS informatics and clinical genomics market and assesses the factors governing the same.
Key Topics Covered:
Executive Summary
1 Market Overview
1.1 Introduction to NGS Informatics and Clinical Genomics
1.2 Cost of NGS Data Analysis
1.3 Role of NGS Informatics in Precision Medicine?
1.4 Approach to Precision Medicine
1.5 Evolution of Precision Medicine Technology
1.6 The Wave of Data Types: NGS Data Remains the Leading Data Type for Precision Medicine
1.6.1 Overview
1.6.2 Genomic Data
1.6.3 Lifestyle and Environment
1.6.4 Health Information
1.6.5 Social Media
1.7 Healthcare Information Technology: A Boon for NGS informatics Market
1.8 The Correlation Between NGS Informatics and Clinical Genomics
1.9 Technologies with the Potential to Incorporate NGS in a Clinical Setting
1.9.1 Electronic Health Records (EHR)
1.9.2 Health Information Exchange
1.9.3 Clinical Decision Support Systems (CDSS)
1.9.4 Population Health Management (PHM)
1.9.5 Blockchain
1.9.6 Artifical Intelligence/Machine Learning
1.9.7 Big Data Analytics
2 Market Dynamics
2.1 Impact Analysis
2.2 Market Drivers
2.2.1 Low cost Sequencing Platforms
2.2.2 Growth in Clinical Application
2.2.3 Rise in Genomic Data
2.2.4 Increasing Number of Population Genomics Initiatives
2.2.5 Advancements in Big Data Technology
2.2.6 Reducing Cost of Cloud Storage
2.3 Market Restraints
2.3.1 Lack of Integration and Interoperability among Existing Information Systems
2.3.2 Patient Access to Data
2.3.3 Data Security and Privacy
2.3.4 Fragmented Research Environment
2.4 Market Opportunities
2.4.1 Cross Industry Collaborations between Health Systems, Academia and Health IT Industry
2.4.2 Investment in Blockchain Technology and Information Security
2.4.3 Clinical Application Focussed NGS Informatics Products
2.4.4 Integration of Clinical and Non-Clinical NGS data
2.4.5 Automation of Sequencing and Interpretation
3 Competitive Insights
3.1 Key Strategies and Developments
3.1.1 Partnerships, Joint Ventures, and Collaborations
3.1.2 Product Development and Launch
3.1.3 Business Funding and Contracts
3.1.4 Mergers and Acquisitions
3.1.5 Approvals and Certifications
3.1.6 Others
3.2 Competitive Scenario: Intense Competition within a Converging Market
4 Industry Attractiveness and Insights
4.1 Porter's Five Forces Analysis
4.2 Bargaining Power of Suppliers
4.3 Bargaining Power of Buyer
4.4 Threat of New Entrants
4.4.1 Threat of Substitute Products
4.4.2 Intensity of Competitive Rivalry
5 Key Industry Insights
5.1 Introduction
5.2 Regulatory Bodies
6 Global NGS Informatics and Clinical Genomics Market: Analysis and Forecast
6.1 Assumptions & Limitations for Market Size Calculations
7 Global NGS Informatics and Clinical Genomics Market (by Technology)
7.1 Overview
7.1.1 Blockchain Genomics Platforms
7.1.2 Data Aggregation Software
7.1.3 AI/Machine Learning and Cloud Computing based Genomic Platforms
7.1.4 Clinical Decision Support based Genomic Platforms
7.1.5 Artificial Intelligence (AI) based Drug Discovery Platforms
8 Global NGS Informatics and Clinical Genomics Market (by Product Type)
8.1 Laboratory Information Management Systems (LIMS)
8.2 NGS Informatics Services (Includes both Sequencing and Consulting Services)
8.3 Commercial Primary and Secondary Data Analysis Tools
8.3.1 Primary Data Analysis
8.3.2 Secondary Data Analysis
8.4 Storage, Infrastructure, and Computing
8.5 Interpretation (Tertiary Analysis) Tools
9 Global NGS Informatics and Clinical Genomics Market (by End User)
9.1 Academics and Research Institutes
9.2 Biopharmaceutical Industry
9.3 Diagnostic Industry
9.4 Government Agencies
9.5 Hospitals and Clinics
10 Global NGS Informatics and Clinical Genomics Market (by Region)
11 Company Profiles
- 2bPrecise, LLC
- Amazon Web Services, Inc.
- Beijing Genomic Institute (BGI)
- Cota, Inc.
- CureMatch, Inc.
- DNASTAR
- DNAnexus, Inc.
- DrChrono Inc.
- Eagle Genomics
- Edico Genome
- Epic Systems Corporation
- F. Hoffmann-La Roche AG
- Fabric Genomics, Inc. (Formerly Omicia, Inc.)
- Flatiron Health, Inc. (Subsidiary of Roche Group Company)
- Genalice
- GenomOncology, LLC
- Genomatix AG
- IBM Corporation
- Illumina, Inc.
- Interpreta, Inc.
- Koninklijke Philips N.V.
- LunaDNA Inc.
- N-of-One, Inc.
- NantHealth, Inc.
- Navican Genomics, Inc.
- Orion Health Group Limited
- Partek Incorporated
- QIAGEN N.V.
- SAP SE
- SOPHiA GENETICS SA
- Seven Bridges Genomics Inc.
- Syapse, Inc.
- Tempus Labs, Inc.
- Verily Life Sciences LLC
- WuxiNextCode
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