Cognition Therapeutics Releases New Episode of “Conversations” Podcast Recorded at CTAD with Quantitative EEG Experts, Drs Willem de Haan and Philip Scheltens

PURCHASE, N.Y., Nov. 16, 2023 (GLOBE NEWSWIRE) -- Cognition Therapeutics, Inc., (Nasdaq: CGTX), (the “Company” or “Cognition”) has released its seventh Conversations video podcast episode: “Quantitative EEG - Effects of CT1812 on Measures of Synaptic Function in Alzheimer’s Disease.” This episode will feature a review and interactive discussion of the results from Cognition’s Phase 2 SEQUEL study, which were presented at the Clinical Trials on Alzheimer’s Disease (CTAD) conference.

During the episode, Cognition Therapeutics’ CMO and head of R&D, Anthony Caggiano, M.D., Ph.D. moderates a discussion with two leading experts:

• Willem de Haan, M.D., Ph.D., Senior Researcher at the Alzheimer Center at Amsterdam University Medical Center
• Philip Scheltens, M.D., Managing Partner at EQT Life Sciences; Founder of the Alzheimer Center at Amsterdam University Medical Center

Dr. de Haan presented the SEQUEL findings at CTAD in a poster that described the positive impact of CT1812 treatment on synaptic function in adults with mild-to-moderate Alzheimer’s disease. There is substantial evidence that quantitative EEG can be used to measure synaptic dysfunction. This measurable dysfunction is observed early in the Alzheimer’s disease process and is correlated with declining cognition. An improvement in synaptic function is therefore considered essential for slowing cognitive decline.

Listen to episode seven, “Quantitative EEG - Effects of CT1812 on Measures of Synaptic Function in Alzheimer’s Disease” on the Conversations tab of the Cognition website.

About the Sequel Study
The SEQUEL study enrolled 16 adults with mild-to-moderate Alzheimer’s disease (MMSE 18-26), each of whom were randomized to receive either CT1812 or placebo once daily for four weeks. After a 14-day wash-out period, participants cross over into the other treatment arm for an additional four weeks. SEQUEL was designed to assess the safety and efficacy of CT1812 and to measure the impact of CT1812 on the electrical activity in the brain, specifically those electrical impulses in the theta band.

SEQUEL was supported by $5.3 million in grant awards (R01AG058710) by the National Institute of Aging (NIA) of the National Institutes of Health (NIH).

About Cognition Therapeutics, Inc.
Cognition Therapeutics, Inc. is a clinical-stage biopharmaceutical company engaged in the discovery and development of innovative, small molecule therapeutics targeting age-related degenerative disorders of the central nervous system and retina. We are currently investigating our lead candidate CT1812 in clinical programs in Alzheimer’s disease, dementia with Lewy bodies (DLB) and dry age-related macular degeneration (dry AMD). We believe CT1812 and our pipeline of σ-2 receptor modulators can regulate pathways that are impaired in these diseases. We believe that targeting the σ-2 receptor with CT1812 represents a mechanism functionally distinct from other current approaches in clinical development for the treatment of degenerative diseases. More about Cognition Therapeutics and its pipeline can be found at https://cogrx.com 

Health Care Disclaimer
Our podcast series does not constitute the practice of medical advice, diagnosis or treatment. Always talk to your health care provider for diagnosis and treatment, including your specific medical needs. If you have or suspect that you have a medical problem or condition, please contact a qualified health care professional immediately.

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